Soft Capsules

PEARLtec technology is a process for obtaining softgel (soft capsules) that makes it possible for a liquid matrix, in a suspension or a gel, to be incorporated into a continuous soft gelatine shell, thereby improving both the oral intake of the medicinal product and patient compliance.

The first step consists in weighing the capsule ingredients, before they are processed using dedicated machines known as turbo emulsifiers. During this part of the process, the optimally balanced excipients are blended together and prepared for the next step.

The heart of the process and of the technology for soft capsules is the encapsulation step (PEARLtec). The mass that will form the capsule shell is hot-extruded into two ribbons that pass through two roller moulds positioned opposite one another, and that give the capsule its shape. A high-precision syringe pump then injects the previously formulated active substance, inside a mass known as filler, into the capsule being moulded.

Soft gels is one of the best pharmaceutical dosage forms.

This makes it possible to obtain tiny transparent beads consisting of two heat-moulded shells.

The advantages are:

1. High dosing precision and better oral bioavailability than other oral solid forms;
2. Excellent dissolution profile, regardless of the pH;
3. Ease of oral administration;
4. Neutral or flavourless taste.